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Collagen Fibers Scaffold Cam Chorioallantoic Membrane Model Os Osteosarcoma Tme Tumour Microenvironment 2d Bidimensional Gs Serial Generations, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Application of <t>PCFS</t> scaffolds loaded with CBD-NT-3 to boost functional neuronal growth and axonal regeneration for the treatment of SCI. (A) Schematic representation of SCI repair using PAO to create a biomimetic collagen scaffold with unique physical properties. (B, C) Immunofluorescence staining maps of Tuj-1 + and Map-2 + in the injured sites of the individual treatment groups. Scale bars: 1 mm (left) and 50 μm (right and below). (D) Quantitative analysis of the area of Tuj-1 + and Map-2 + cells at the injury site in the different treatment groups. * P < 0.05, ** P < 0.01, *** P < 0.001. Reprinted with permission from Zhao et al. (2024). Copyright 2024 Wiley‐VCH GmbH. CBD-NT-3: Collagen-binding domain-neurotrophin-3; DAPI: 4′,6-diamidino-2-phenylindole; EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; LOCS: linear ordered collagen scaffolds; Map-2: microtubule-associated protein-2; NHS: N-hydroxysuccinimide; NSC: neural stem cell; PAO: plasma amine oxidase; PCFS: porous collagen fibers; SCI: spinal cord injury.
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Application of <t>PCFS</t> scaffolds loaded with CBD-NT-3 to boost functional neuronal growth and axonal regeneration for the treatment of SCI. (A) Schematic representation of SCI repair using PAO to create a biomimetic collagen scaffold with unique physical properties. (B, C) Immunofluorescence staining maps of Tuj-1 + and Map-2 + in the injured sites of the individual treatment groups. Scale bars: 1 mm (left) and 50 μm (right and below). (D) Quantitative analysis of the area of Tuj-1 + and Map-2 + cells at the injury site in the different treatment groups. * P < 0.05, ** P < 0.01, *** P < 0.001. Reprinted with permission from Zhao et al. (2024). Copyright 2024 Wiley‐VCH GmbH. CBD-NT-3: Collagen-binding domain-neurotrophin-3; DAPI: 4′,6-diamidino-2-phenylindole; EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; LOCS: linear ordered collagen scaffolds; Map-2: microtubule-associated protein-2; NHS: N-hydroxysuccinimide; NSC: neural stem cell; PAO: plasma amine oxidase; PCFS: porous collagen fibers; SCI: spinal cord injury.
Af Scaffold With Oriented Cross Fibers, supplied by BioMimetic Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Application of <t>PCFS</t> scaffolds loaded with CBD-NT-3 to boost functional neuronal growth and axonal regeneration for the treatment of SCI. (A) Schematic representation of SCI repair using PAO to create a biomimetic collagen scaffold with unique physical properties. (B, C) Immunofluorescence staining maps of Tuj-1 + and Map-2 + in the injured sites of the individual treatment groups. Scale bars: 1 mm (left) and 50 μm (right and below). (D) Quantitative analysis of the area of Tuj-1 + and Map-2 + cells at the injury site in the different treatment groups. * P < 0.05, ** P < 0.01, *** P < 0.001. Reprinted with permission from Zhao et al. (2024). Copyright 2024 Wiley‐VCH GmbH. CBD-NT-3: Collagen-binding domain-neurotrophin-3; DAPI: 4′,6-diamidino-2-phenylindole; EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; LOCS: linear ordered collagen scaffolds; Map-2: microtubule-associated protein-2; NHS: N-hydroxysuccinimide; NSC: neural stem cell; PAO: plasma amine oxidase; PCFS: porous collagen fibers; SCI: spinal cord injury.
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Application of <t>PCFS</t> scaffolds loaded with CBD-NT-3 to boost functional neuronal growth and axonal regeneration for the treatment of SCI. (A) Schematic representation of SCI repair using PAO to create a biomimetic collagen scaffold with unique physical properties. (B, C) Immunofluorescence staining maps of Tuj-1 + and Map-2 + in the injured sites of the individual treatment groups. Scale bars: 1 mm (left) and 50 μm (right and below). (D) Quantitative analysis of the area of Tuj-1 + and Map-2 + cells at the injury site in the different treatment groups. * P < 0.05, ** P < 0.01, *** P < 0.001. Reprinted with permission from Zhao et al. (2024). Copyright 2024 Wiley‐VCH GmbH. CBD-NT-3: Collagen-binding domain-neurotrophin-3; DAPI: 4′,6-diamidino-2-phenylindole; EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; LOCS: linear ordered collagen scaffolds; Map-2: microtubule-associated protein-2; NHS: N-hydroxysuccinimide; NSC: neural stem cell; PAO: plasma amine oxidase; PCFS: porous collagen fibers; SCI: spinal cord injury.
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Application of <t>PCFS</t> scaffolds loaded with CBD-NT-3 to boost functional neuronal growth and axonal regeneration for the treatment of SCI. (A) Schematic representation of SCI repair using PAO to create a biomimetic collagen scaffold with unique physical properties. (B, C) Immunofluorescence staining maps of Tuj-1 + and Map-2 + in the injured sites of the individual treatment groups. Scale bars: 1 mm (left) and 50 μm (right and below). (D) Quantitative analysis of the area of Tuj-1 + and Map-2 + cells at the injury site in the different treatment groups. * P < 0.05, ** P < 0.01, *** P < 0.001. Reprinted with permission from Zhao et al. (2024). Copyright 2024 Wiley‐VCH GmbH. CBD-NT-3: Collagen-binding domain-neurotrophin-3; DAPI: 4′,6-diamidino-2-phenylindole; EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; LOCS: linear ordered collagen scaffolds; Map-2: microtubule-associated protein-2; NHS: N-hydroxysuccinimide; NSC: neural stem cell; PAO: plasma amine oxidase; PCFS: porous collagen fibers; SCI: spinal cord injury.
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Constructing SDBVs with 3D printing.
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Constructing SDBVs with 3D printing.
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Application of PCFS scaffolds loaded with CBD-NT-3 to boost functional neuronal growth and axonal regeneration for the treatment of SCI. (A) Schematic representation of SCI repair using PAO to create a biomimetic collagen scaffold with unique physical properties. (B, C) Immunofluorescence staining maps of Tuj-1 + and Map-2 + in the injured sites of the individual treatment groups. Scale bars: 1 mm (left) and 50 μm (right and below). (D) Quantitative analysis of the area of Tuj-1 + and Map-2 + cells at the injury site in the different treatment groups. * P < 0.05, ** P < 0.01, *** P < 0.001. Reprinted with permission from Zhao et al. (2024). Copyright 2024 Wiley‐VCH GmbH. CBD-NT-3: Collagen-binding domain-neurotrophin-3; DAPI: 4′,6-diamidino-2-phenylindole; EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; LOCS: linear ordered collagen scaffolds; Map-2: microtubule-associated protein-2; NHS: N-hydroxysuccinimide; NSC: neural stem cell; PAO: plasma amine oxidase; PCFS: porous collagen fibers; SCI: spinal cord injury.

Journal: Neural Regeneration Research

Article Title: Biomaterial-based strategies: a new era in spinal cord injury treatment

doi: 10.4103/NRR.NRR-D-24-00844

Figure Lengend Snippet: Application of PCFS scaffolds loaded with CBD-NT-3 to boost functional neuronal growth and axonal regeneration for the treatment of SCI. (A) Schematic representation of SCI repair using PAO to create a biomimetic collagen scaffold with unique physical properties. (B, C) Immunofluorescence staining maps of Tuj-1 + and Map-2 + in the injured sites of the individual treatment groups. Scale bars: 1 mm (left) and 50 μm (right and below). (D) Quantitative analysis of the area of Tuj-1 + and Map-2 + cells at the injury site in the different treatment groups. * P < 0.05, ** P < 0.01, *** P < 0.001. Reprinted with permission from Zhao et al. (2024). Copyright 2024 Wiley‐VCH GmbH. CBD-NT-3: Collagen-binding domain-neurotrophin-3; DAPI: 4′,6-diamidino-2-phenylindole; EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; LOCS: linear ordered collagen scaffolds; Map-2: microtubule-associated protein-2; NHS: N-hydroxysuccinimide; NSC: neural stem cell; PAO: plasma amine oxidase; PCFS: porous collagen fibers; SCI: spinal cord injury.

Article Snippet: Zhao et al. (2024) developed a dual-network porous collagen fiber (PCFS) scaffold for neurogenesis using a combination of biomimetic plasma ammonia oxidase catalysis and conventional amide cross-linking.

Techniques: Functional Assay, Immunofluorescence, Staining, Binding Assay, Clinical Proteomics

Constructing SDBVs with 3D printing.

Journal: Small Science

Article Title: Stem‐Cell‐Based Small‐Diameter Blood Vessels with 3D Printing

doi: 10.1002/smsc.202400261

Figure Lengend Snippet: Constructing SDBVs with 3D printing.

Article Snippet: MSCs , The circumferential fiber scaffold was designed to biomimetic autologous vascular compliance and provide suitable microcues for MSC proliferation and migration to realize the early accumulation of ECM components in the scaffold , The design of ECM components in the bionic body of the fiber structure realizes the close combination of the structure–function relationship by reforming mechanical energy , Klein et al. [ ] .

Techniques: Diffusion-based Assay, Activity Assay, In Vitro, In Vivo, Construct, Transplantation Assay, Migration